Exploring Challenges In Sequence To Expression Modeling

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Saurabh Sinha, University of Illinois, Urbana‑Champaign Regulatory Genomics and Epigenomics ... Genomic MIT 7.91J Foundations of Computational and Systems Biology, Spring 2014 View the complete course: ... We move beyond CpG islands and start to discuss another application of HMMs in genomics: finding genes! Finding genes is not ...

Step by step, we create an HMM for gene finding. We first discuss why the eukaryotic gene finding problem is the truly hard one, ...

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